Delivery of oxygen during cardiopulmonary bypass and associated clinical outcomes among adult cardiac surgery patients: A systematic review.

ABSTRACT: PurposeOxygen delivery (DO₂) during cardiopulmonary bypass (CPB) is critical in preventing postoperative complications in adult cardiac surgery. This systematic review aimed to assess the relationship between intraoperative DO₂ during CPB, particularly within Goal-directed Perfusion (GDP) strategies, and associated clinical outcomes.MethodsA systematic search of MEDLINE, Embase, Web of Science, PsycINFO, CINAHL, PROSPERO, and Cochrane was conducted from database inception through December 2024, adhering to PRISMA 2020 guidelines. Studies reported intraoperative DO₂ measurements and their relationship with clinical outcomes among adults undergoing cardiac surgery with CPB. Data extraction and quality assessment were performed independently by two reviewers.R

SUBMITTER: Dias RD 

PROVIDER: S-EPMC12715685 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature