Accelerometer-measured weekend catch-up sleep and incident dementia: A prospective cohort study.

ABSTRACT:

Introduction

Healthy sleep may support cognitive health, but the role of weekend catch-up sleep is unclear.

Methods

Among 83,776 dementia-free UK Biobank participants aged ≥50 years, sleep duration was estimated from 7-day accelerometer data (2013-2015). Weekend catch-up sleep was defined as the weekend-weekday sleep duration difference. Cox regression model was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause dementia associated with weekend catch-up sleep.

Results

During follow-up (median: 8.0 years), 713 participants developed all-cause dementia. Compared with ≤0.5 h, HRs for all-cause dementia across catch-up sleep categories were 0.91 (0.74-1.11) for > 0.5-1 h, 0.64 (0.49-0.86) for > 1-1.5 h, 0.84 (0.60-1.16) for > 1.5-2 h, an

SUBMITTER: Chen H 

PROVIDER: S-EPMC12715702 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature