Global, regional, and national burden of brain and central nervous system cancer in children and adolescents, 1990-2021: A systematic analysis of the Global Burden of Disease study 2021.

ABSTRACT:

Importance

Brain and central nervous system (CNS) cancers are the most common pediatric solid tumors, significantly affecting the patients' life expectancy and quality.

Objective

To examine the disease burden of brain and CNS cancer in children and adolescents from 1990 to 2021 across various age groups, sexes, and socio-demographic index levels, at the global, regional, and national levels.

Methods

Data, including the incidence, mortality, and disability-adjusted life years (DALYs) of brain and CNS cancer in children and adolescents, were obtained from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study. Temporal trends were evaluated using the Joinpoint regression model. The relationship between disease burden and socioeconomic development, as well

SUBMITTER: Deng Y 

PROVIDER: S-EPMC12715896 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature