Larvicidal Activity of Phytochemicals From Handroanthus impetiginosus Seeds Against Culex quinquefasciatus.

ABSTRACT: Handroanthus impetiginosus is a species known to produce bioactive substances, including compounds with larvicidal activity. This study evaluated the toxicity of hexane extract (HE), fatty acids (FAs), and FA methyl esters (FAMEs) from H. impetiginosus seeds against Culex quinquefasciatus larvae. FAs were obtained by hydrolysis of triglycerides present in HE for 30 and 60 min, and FAMEs were produced by transesterification of FAs for the same time. HE was analyzed by gas chromatography-mass spectrometry (GC-MS). Oleic acid and ethyl oleate were found in abundance in HE. HE, FA30s, and FA60s produced mortality rates above 90% in C. quinquefasciatus larvae; FA60s produced a 100% mortality rate at the highest concentration at which they were tested (250 µg/mL). LD₅₀ values ranged f

SUBMITTER: Santos LCD 

PROVIDER: S-EPMC12715983 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature