Chemical Composition, Antioxidant, and Antibacterial Activities of Mezilaurus duckei (Lauraceae).

ABSTRACT: Mezilaurus duckei, a Brazilian endemic tree species found exclusively in the Amazon Rainforest, is primarily exploited for timber in construction. Due to its endangered status, this study aimed to investigate the chemical profile and biological properties of the ethanolic extract and its phases derived from M. duckei leaves. Chemical profiling using high-performance liquid chromatography-tandem mass spectrometry revealed flavonoids, including glycosylated kaempferol and its derivatives, as well as γ-butyrolactones, as the major constituents. Additional chromatographic separations led to the isolation of kaempferol, reported for the first time in the Mezilaurus genus, and rubrenolide, identified for the first time in M. duckei. Antioxidant activity, assessed using the 2,2-diphenyl-1-picrylh

SUBMITTER: Moroto BS 

PROVIDER: S-EPMC12715993 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature