Transcriptome and metabolome analysis of <i>Atractylodes lancea</i> across different developmental stages.

ABSTRACT: Atractylodes lancea (Thunb.) DC is a medicinal plant known for its rhizome's production of valuable sesquiterpenoids, although the molecular mechanisms underlying their biosynthesis are not well understood. This study utilized integrated metabolomic and transcriptomic analyses to examine terpenoid dynamics across four developmental stages (June, July, September, November) in A. lancea. Metabolite profiling indicated distinct accumulation patterns: monoterpenoids reached their peak in July, while sesquiterpenoids were most abundant in September. Transcriptome analysis revealed the presence of 36 structural genes linked to the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, alongside 55 terpene synthase (TPS) genes. Subsequent phylogenetic analysis categorized t

SUBMITTER: Zhang G 

PROVIDER: S-EPMC12716082 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature