Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex.

ABSTRACT: Wireless neuromodulation technologies aim to eliminate the need for invasive hardware and enhance tissue compatibility. Magnetoelectric (ME) materials enable magnetic field-induced electrical stimulation, offering a minimally invasive neural activation. However, conventional ME systems use rigid ceramic components with limited biocompatibility. Here, a flexible, predominantly organic ME platform composed of polyvinylidene fluoride (PVDF) nanofibers embedded with anisotropic magnetite nanodiscs (MNDs) is reported. These MNDs are selected for their unique ability to exert magnetic torque due to vortex magnetization and their intrinsic magnetostrictive behaviour. The resulting ME fibers preserve the piezoelectric β-phase of PVDF and exhibit a magnetoelectric voltage coefficient of 1.26 Vcm

SUBMITTER: Signorelli L 

PROVIDER: S-EPMC12716173 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature