Superferromagnetic Disk Particles for Magnetic Particle Imaging.

ABSTRACT: Magnetic particle imaging (MPI) offers rapid, highly sensitive tracer-based imaging without ionizing radiation, but its clinical translation remains challenged by the limited performance of existing superparamagnetic (SP) tracers. In this work, precisely engineered disk-shaped nanoparticles fabricated from superferromagnetic (SF) discontinuous metal-insulator multilayers (DMIMs) consisting of SP nanoscale metal islands embedded in a nonmagnetic oxidic matrix are introduced. By leveraging inter-island exchange interactions, robust SF behavior is achieved in extended DMIMs, exhibiting exceptionally high susceptibilities and a sharp magnetization switching at fields below 1 mT. When evaluated in MPI experiments, magnetic disk particles (MDP) with a diameter of 1800 nm patterned from the SF DM

SUBMITTER: Mayr EM 

PROVIDER: S-EPMC12716192 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature