Serum vitamin D and calcium levels among tuberculosis patients in Southern Ethiopia: a comparative cross-sectional study.

ABSTRACT:

Objectives

To compare serum vitamin D and calcium levels between tuberculosis (TB) patients and age-matched and sex-matched healthy controls, and to evaluate their relationship with disease severity.

Design

Comparative cross-sectional study.

Setting

Dilla University Teaching Hospital (DUTH), Southern Ethiopia.

Participants

100 adult TB patients and 100 age-matched and sex-matched healthy controls aged 18 years or over.

Primary outcome measures

Serum 25-hydroxyvitamin D [25(OH)D] and calcium levels.

Results

Mean serum vitamin D was markedly lower in TB patients than in controls (21.4±7.3 ng/mL vs 32.0±6.6 ng/mL; p<0.001), with 45% of TB patients classified as deficient. Similarly, serum calcium levels were decreased among TB patients (9.09±0.43 mg/

SUBMITTER: Robsha Oshe O 

PROVIDER: S-EPMC12716536 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature