To assess the clinical utility of composite outcomes in studies examining outcomes of implantable neuromodulation therapies for pain: a systematic review.

ABSTRACT:

Background

Implantable neuromodulation therapies are offered to patients with certain refractory pain syndromes. These therapies are resource-intensive and effort-intensive and may be associated with significant adverse effects. Change in pain intensity score, an unidimensional measurement tool, is currently the most used eligibility criteria for patients to receive implanted neuromodulation devices. However, pain is a biopsychosocial phenomenon, and assessment of effectiveness of neuromodulation therapies using tools that incorporate multiple pain-related domains may be more relevant and accurate. Composite measures integrate multiple domains of patient well-being, enabling a clinically relevant assessment of treatment effects. This systematic review aims to evaluate the literatur

SUBMITTER: Chung OS 

PROVIDER: S-EPMC12716540 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature