Burden of herpes zoster among patients with systemic lupus erythematosus in the USA.

ABSTRACT:

Objective

To estimate the incidence of herpes zoster (HZ) and the incremental healthcare resource utilisation (HRU) and costs associated with HZ among adults with systemic lupus erythematosus (SLE).

Methods

This retrospective cohort study included insured patients from 2015 to 2022. HZ incidence rates were estimated among patients with SLE, SLE without other immunocompromising conditions (ICC) (SLE only) and no ICC. Adjusted incidence rate ratios (aIRRs) and 95% confidence intervals (CIs) comparing the SLE and SLE only cohorts versus the no ICC cohort were estimated using Poisson regression. All-cause HRU and costs were compared between patients with SLE and HZ (SLE+/HZ+) and propensity score matched patients with SLE without HZ (SLE+/HZ-).

Results

The incidence rates

SUBMITTER: Stempniewicz N 

PROVIDER: S-EPMC12716564 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature