Understanding barriers and enablers for vaccination against COVID-19 and influenza among healthcare workers: a mixed-methods study nested within the UK SIREN cohort.

ABSTRACT:

Objectives

To investigate vaccination coverage for influenza and COVID-19 in the SARS-CoV-2 immunity and reinfection evaluation (SIREN) study cohort of healthcare workers (HCWs) between 2020 and 2023 and explore vaccination enablers and barriers.

Design

A mixed-methods study nested within SIREN, a multicentre prospective cohort study of HCWs across the UK. Quantitative and qualitative methods were used sequentially, using an expansion/explanation function, enabling emergent themes observed from the quantitative stage to be explored in the qualitative stage.

Setting

SIREN sites include secondary care centres and community mental health trusts in the UK.

Participants

Quantitative analysis was conducted on data from 6048 participants. Participants were representat

SUBMITTER: Sparkes D 

PROVIDER: S-EPMC12716576 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature