Oral PrEP continuation rates among key populations in Nigeria: a retrospective cohort study of a large-scale HIV prevention programme.

ABSTRACT:

Introduction

Pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy, but its impact is limited by low uptake and poor continuation rates. This study investigates oral PrEP continuation among key populations (KPs) enrolled in an HIV prevention programme across seven states in Nigeria, representing one of the largest longitudinal PrEP continuation studies in Sub-Saharan Africa to date.

Methods

We analysed data from 43 788 clients who initiated daily oral PrEP between January 2020 and March 2023. The sample comprised female sex workers (20 574, 47.0%), men who have sex with men (12 946, 29.6%), people who inject drugs (9462, 21.6%) and transgender individuals (806, 1.8%). The primary outcome was 6-month PrEP continuation, defined as having a recorded PrEP refil

SUBMITTER: Nwosu KD 

PROVIDER: S-EPMC12716584 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature