Effect of autologous amniotic membrane and fluid on wound healing and complications of cesarean section: Study protocol of a factorial randomized controlled trial.

ABSTRACT:

Background

Cesarean section rates have risen globally. While a cesarean section offers benefits, it is associated with complications like infection, fluid collection, and wound dehiscence. The psychological impact of cesarean section scars can also affect women's quality of life. Amniotic membrane and fluid have shown promise in enhancing wound healing due to their rich content of growth factors and nonimmunogenic properties. This study aims to assess the effects of autologous amniotic membrane and amniotic fluid on wound healing, surgical site infection, pain, and complications following cesarean section.

Materials and methods

This controlled, randomized, double-blind (participants and the physician assessing outcomes are blinded), 2 × 2 factorial trial with a sample size o

SUBMITTER: Jafari K 

PROVIDER: S-EPMC12716681 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature