The cost-effectiveness of penicillin allergy testing: Evidence and gaps from a systematic review.

ABSTRACT:

Introduction

Patients with a penicillin allergy label (PAL) use more and broader-spectrum antibiotics, have worse health outcomes and cost more to treat than patients without a PAL. A significant proportion of penicillin allergy labels are incorrect; here we review the published evidence on the costs, health-related quality of life, and cost-effectiveness of penicillin allergy testing.

Methods

We conducted a systematic review of published economic evaluations of penicillin allergy testing in accordance with Cochrane guidelines. We searched Medline, Embase, Scopus, Web of Science, EconPapers (RePeC) and the International HTA Database (INAHTA) and included reports of full or partial economic evaluations of costs and/or health benefits of penicillin allergy testing strategies.

SUBMITTER: Mujica-Mota RE 

PROVIDER: S-EPMC12716781 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature