Ligand-to-Metal Charge Transfer of Ag(II) CF₂X Carboxylates: Quantum Yield and Electrophotocatalytic Arene Fluoroalkylation Tuned by X.

ABSTRACT: Incorporation of CF₂X groups beyond CF₃ into arene scaffolds is underdeveloped despite these groups' utility as halogen-bond donors and as precursors to bioisosteres. Herein, we report the synthesis, characterization, and comparative photochemistry of a suite of [Ag(II)(bpy)₂O₂CCF₂X]⁺ and Ag(II)(bpy)(O₂CCF₂X)₂ (bpy = 2,2´-bipyridine, X = F, CF₃, Cl, Br, H, CH₃) carboxylate complexes. We find a dramatic effect of the X substituent on the efficiency of generating CF₂X radicals by ligand-to-metal charge transfer (LMCT), with Ag(II) photoreduction rates varying by over an order of magnitude and quantum yields spanning over 20%. We provide insight into how electron

SUBMITTER: Campbell BM 

PROVIDER: S-EPMC12716939 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature