Assessing the Impact of Whole Genome Duplication on Gene Expression and Regulation During Arachnid Development.

ABSTRACT: Whole genome duplication (WGD) generates a new genetic material that can contribute to the evolution of developmental processes and phenotypic diversification. A WGD occurred in an ancestor of arachnopulmonates (spiders, scorpions, and their relatives), which provides an important independent comparison to WGDs in other animal lineages. After WGD, arachnopulmonates retained many duplicated copies (ohnologues) of developmental genes including clusters of homeobox genes, many of which have been inferred to have undergone subfunctionalization. However, there has been little systematic analysis of gene regulatory sequences and comparison of the expression of ohnologues versus their single-copy orthologues between arachnids. Here, we compare the regions of accessible chromatin and gene expressi

SUBMITTER: Aase-Remedios ME 

PROVIDER: S-EPMC12717030 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature