Carbon isotope effects in cometabolic oxidation of halogenated organics by a methanotroph.
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ABSTRACT: Cometabolic oxidation is a process in which compounds, including groundwater pollutants such as halogenated aliphatics, are fortuitously oxidized by enzymes with broad substrate specificity. Assessing the magnitude of cometabolic oxidation in contaminated environments is challenging; however, it may be facilitated using Compound-Specific Isotope Analysis. Our former work on the cometabolic oxidation of trichloroethene (TCE) revealed a unique isotope pattern when the process was catalyzed by several methanotrophs rather than by toluene and ammonia oxidizers. In the current work, we aimed to study isotope effects in the cometabolic oxidation of other halogenated compounds of environmental interest by the methanotroph Methylosinus trichosporium OB3b. Results showed relatively small carbon iso
SUBMITTER: Rauniyar P
PROVIDER: S-EPMC12717205 | biostudies-literature | 2025 Nov
REPOSITORIES: biostudies-literature
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