Acute effects of resistance exercise on skeletal muscle glycogen depletion: A systematic review and meta-analysis.

ABSTRACT: To compile and statistically summarize quantitative evidence on the acute effects of resistance training sessions on muscle glycogen concentration, a systematic search was conducted on Pubmed, Web of Science, and Scopus databases up to 28th July 2024. Twenty studies including 168 male and 12 female participants were eligible. A multilevel, random-effects meta-analysis was used to calculate the overall mean difference (MD) with a 95% confidence interval (CI) and prediction interval (PI). The model (28 effect sizes across 20 clusters) revealed a significant glycogen decrease (MD = -104.3; 95% CI: -137.6 to -71.0; PI: -244.4 to 35.7; p < 0.001). Meta-regression showed greater depletion with more sets (Estimate = -11.2; 95% CI: -18.0 to -4.3; p = 0.001) and longer session duration (Estimate = 

SUBMITTER: Hamidvand A 

PROVIDER: S-EPMC12717450 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature