Unhealthy diet quality as a clinical phenotype in bipolar disorder: A potential treatment target for improved mood and metabolic outcomes.

ABSTRACT:

Objectives

This study aimed to investigate unhealthy diet quality in bipolar disorder (BD) and its association with social, metabolic and clinical features in a cohort of well-characterized adult patients with BD.

Methods

This study analyzed a subset of 737 adult participants from the Mayo Clinic Bipolar Disorder Biobank (MCBB) who completed the Rapid Eating Assessment for Participants - Shortened Version (REAP-S) diet quality questionnaire, in which scores <32 indicate an unhealthy diet quality (UDQ). Demographic and clinical variables were compared between individuals with unhealthy and healthy diet quality. Regression models were constructed to explore associations between UDQ and demographic variables, bipolar subtype, chronotype, medical comorbidities, psychotropics and

SUBMITTER: Gardea-Resendez M 

PROVIDER: S-EPMC12717528 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature