Trends and disparities in chronic ischemic heart disease mortality among adult cancer patients: a nationwide CDC WONDER analysis (1999-2020).

ABSTRACT:

Background

Chronic ischemic heart disease (IHD) is a leading cause of cardiovascular-related mortality worldwide, with a growing burden among cancer patients due to shared risk factors and treatment-related Cardiotoxicity. However, nationwide trends and disparities in IHD-related mortality among cancer patients remain unexplored.

Methodology

This study utilized CDC WONDER mortality data from 1999 to 2020, identifying U.S. adults (≥ 25 years) with cancer (ICD-10: C00-D48) who died from chronic IHD (ICD-10: I25) as the underlying cause. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were calculated and stratified by gender, age, race, geographic region, and urbanization level.

Results

Between 1999 and 2020, there were 246,664 Chronic IHD-related

SUBMITTER: Qasim SA 

PROVIDER: S-EPMC12717754 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature