Right Ventricular-Pulmonary Arterial Uncoupling Thresholds in Acute Pulmonary Embolism.

ABSTRACT:

Introduction/purpose

Right ventricle (RV) dysfunction in the setting of acute pulmonary embolism (PE) is associated with worse outcomes. The ratio of tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery systolic pressure (PASP) provides an estimate of right ventricular-arterial (RV-PA) coupling and has been associated with adverse outcomes in patients with pulmonary hypertension. In this study, we examined if RV-PA uncoupling can further risk stratify acute PE.

Methods

This is a single-center, retrospective analysis of patients admitted to a tertiary center with the diagnosis of acute PE. The Kruskal-Wallis Rank Sum, Wilcoxon Rank Sum, and Chi-square tests were used to identify clinical features associated with reduced RV-PA uncoupling at three distinct th

SUBMITTER: Zeba F 

PROVIDER: S-EPMC12718099 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature