Efficacy of 4 % deltamethrin-impregnated collars against canine visceral leishmaniasis across different areas and the sociocultural burden of collar loss in a middle-income country.

ABSTRACT: Despite efforts to control visceral leishmaniasis (VL), the disease remains a major burden in low- and middle-income countries. In South America, insecticide-impregnated dog collars help prevent disease transmission, as dogs are the main reservoirs in urban areas. This study evaluated the efficacy of 4 % deltamethrin-impregnated collars (DMC) against canine VL (CVL) over a 24-month period in an endemic area of Brazil. We compared 941 DMC dogs with 1032 control dogs (C) across four geographic areas with similar baseline disease prevalence. The difference between the DMC and C cohorts was statistically significant (p < 0.05), and the study achieved an overall efficacy of 63 %, 51 %, 48 %, and 58 % at the first, second, third, and fourth follow-ups, respectively. Among dogs that remain

SUBMITTER: Matsumoto PSS 

PROVIDER: S-EPMC12718145 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature