Prognostic Role of Adjuvant Radiotherapy in Patients With pT1-2N1-2b Oropharyngeal Squamous Cell Carcinoma.

ABSTRACT: ImportanceThe necessity of adjuvant radiotherapy in patients with pT1-2N1-2b oropharyngeal squamous cell carcinoma (OPSCC) remains unclear.ObjectiveTo examine the prognostic role of adjuvant radiotherapy in patients with either p16-positive or p16-negative pT1-2N1-2b OPSCC.DesignRetrospective study.SettingSurveillance, Epidemiology, and End Results database.ParticipantsPatients diagnosed between 2010 and 2015 with either p16-positive or p16-negative T1-2N1-2bM0 OPSCC who received primary surgery with neck dissection with or without adjuvant radiotherapy were screened for inclusion.InterventionPrimary surgery with neck dissection with or without adjuvant radiotherapy.Main Outcomes and MeasuresOverall survival (OS) and disease-specific survival (DSS) were main outcomes. The overlap propensit

SUBMITTER: Peng L 

PROVIDER: S-EPMC12718343 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature