Long-term impact of cholecystectomy on myocardial infarction, ischemic cerebrovascular accident, and peripheral vascular disease: insights from a nationwide analysis.

ABSTRACT:

Introduction

Acute myocardial infarction (MI), ischemic cerebrovascular accident (CVA), and peripheral vascular disease (PVD) are significant global health burdens that have been associated with cholelithiasis by multiple studies. However, the relationship between cholecystectomy and these vascular morbidities remains unclear. This study aims to investigate the long-term impact of cholecystectomy on MI, CVA and PVD.

Methods

This nationwide study analyzed data, which accounted for 59% of the Israeli population. Adult patients with cholelithiasis and no prior vascular morbidity (MI, CVA, and PVD) were followed for over 8 years and categorized into two groups: those who underwent cholecystectomy and those who did not. Incidence rates of MI, ischemic CVA (including transient isc

SUBMITTER: Messer N 

PROVIDER: S-EPMC12718586 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature