Insufficient pretransplant induction therapy is associated with diffuse intrahepatic cholangiopathy in ABO-incompatible living donor liver transplantation for acute liver failure.

ABSTRACT:

Background

ABO-incompatible liver transplantation (ABOi LT) can now be successfully performed using standard pretransplant induction therapy. ABOi LT can achieve long-term outcomes comparable to those of blood type-compatible (ABOc) LT. The outcomes of patients with acute liver failure (ALF) undergoing urgent transplantation surgery with a limited induction period require further investigation.

Methods

Between 2004 and 2023, adult patients who underwent living donor liver transplantation (LDLT) at Taipei Veterans General Hospital were included in this study. Patients were categorized into four groups for outcome analysis based on the chronicity of liver disease and transplant type. ALF patients who received ABOi LDLT, ALF patients who received ABOc LDLT, ESLD patients who re

SUBMITTER: Hu CY 

PROVIDER: S-EPMC12718781 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature