Feasibility estimation of injected hydrodissection before definitive radiotherapy of pancreatic adenocarcinoma.

ABSTRACT:

Background

Pancreatic adenocarcinoma is often not diagnosed until an advanced stage, and so most patients are not eligible for resection. For patients who are inoperable, definitive radiotherapy is crucial for local disease control. However, the pancreas is located close to other vulnerable gastrointestinal organs, making it challenging to deliver an adequate radiation dose. The surgical insertion of spacers or injection of fluids such as hydrogel before radiotherapy has been proposed, however, no study has discussed which patients are suitable for the procedure.

Methods

In this study, we reviewed 50 consecutive patients who received definitive radiotherapy at our institute to determine how many could have benefitted from hydrodissection to separate the pancreatic tumor from

SUBMITTER: Wu YH 

PROVIDER: S-EPMC12718822 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature