Clinical Utility of Magnetoencephalography in Epilepsy Evaluation: A Qualitative Systematic Review.

ABSTRACT: Magnetoencephalography (MEG) is a non-invasive neurophysiological technique offering high spatial resolution for localizing epileptogenic zones in epilepsy, especially when traditional electroencephalography or magnetic resonance imaging (MRI) is inconclusive. A systematic evaluation of MEG's diagnostic and prognostic utility within combination strategies is crucial, particularly in countries like South Korea with limited MEG access. We conducted a qualitative systematic review of nine studies (n=354 focal epilepsy patients) to evaluate MEG's clinical performance in presurgical workup. Databases (MEDLINE, EMBASE, Cochrane, KoreaMed, KMbase, RISS) were searched. Data extraction focused on localization accuracy and surgical outcomes (Engel class I); risk of bias was assessed using quality as

SUBMITTER: Kim HS 

PROVIDER: S-EPMC12718839 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature