Low preoperative serum uric acid is associated with early acute kidney injury after living donor liver transplantation.

ABSTRACT:

Background

Liver transplantation is treatment option for patients with end-stage liver disease and hepatocellular carcinoma. Renal function deterioration significantly impacts the survival rates of liver recipients, and serum uric acid (SUA) is associated with both acute and chronic renal function disorders. Thus, our study aimed to assess the relationship and predictive value of preoperative SUA level and postoperative acute kidney injury (AKI) in living donor liver transplantation (LDLT).

Methods

We conducted a prospective observational study on 87 patients undergoing LDLT. Blood samples were collected immediately before LDLT, and renal function status was followed up for 3 consecutive days postoperatively.

Results

Low SUA levels (cutoff value 4.15 mg/dL) were assoc

SUBMITTER: Wu YT 

PROVIDER: S-EPMC12718875 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature