Updates on the role of miR-193b in the pathogenesis of human cancers and other diseases.

ABSTRACT: MicroRNAs (miRNAs) have emerged as pivotal regulators of gene expression, fundamentally influencing cellular processes such as proliferation, differentiation, and apoptosis. Among these, miR-193b has garnered significant attention as a potent tumor suppressor in some contexts, while functioning as an oncogene in other situations. Its frequent loss in some types of cancers such as gastric and cervical cancers as well as osteosarcoma positions it not only as a valuable prognostic indicator but also as a potential tool for gene therapy. On the other hand, it has been found to be up-regulated in esophageal and bladder cancers. Meanwhile, data regarding its expression pattern in some types of cancers, such as colorectal, lung and pancreatic cancers is conflicting. Moreover, its influence extend

SUBMITTER: Khalilian S 

PROVIDER: S-EPMC12719069 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature