Clinical effectiveness and cost-effectiveness of two sodium fluoride varnish systems in preventing dental caries in children: a randomized clinical trial.

ABSTRACT:

Background

Dental caries frequently affects first permanent molars soon after eruption due to their anatomical susceptibility. Fluoride varnish is a widely accepted preventive measure; however, different formulations vary in fluoride retention and cost. Evidence comparing both clinical outcomes and economic value of available varnishes in children remains limited.

Aim

To compare the clinical effectiveness and cost-effectiveness of resin-based and alcohol-based 5 % sodium fluoride varnishes in preventing dental caries in permanent first molars of high-risk schoolchildren.

Design

A double-blind, parallel-arm randomized controlled trial was conducted among 84 children (330 M) aged 6-8 years from a private school in Varanasi, India. Participants received either resin-base

SUBMITTER: Khairnar MR 

PROVIDER: S-EPMC12719153 | biostudies-literature | 2026 Jan-Feb

REPOSITORIES: biostudies-literature