Triglyceride-glucose index predicts early, short-term, and long-term mortality after transcatheter aortic valve replacement.

ABSTRACT:

Background

Despite transforming care for severe aortic stenosis, TAVR is still followed by early and late mortality. The triglyceride-glucose (TyG) index, an insulin-resistance marker from routine triglyceride and glucose levels, may flag high-risk patients in Ashkenazi-Jewish and Mediterranean individuals. We examined whether baseline TyG predicts all-cause mortality at 30 days, 1 year, and 3 years post-TAVR.

Methods

We retrospectively studied patients with severe symptomatic aortic stenosis who underwent TAVR at a single tertiary center between 2010 and 2024. The TyG index was calculated from baseline triglyceride and glucose values. The primary endpoint was all-cause mortality at 1 year, with secondary endpoints of all-cause mortality at 30 days and 3 years. Cox proportio

SUBMITTER: Abu Khadija H 

PROVIDER: S-EPMC12719212 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature