Perioperative Management of Hereditary Antithrombin Deficiency in a Patient Undergoing Minimally Invasive Thoracic Surgery: A Case Report.

ABSTRACT:

Introduction

Hereditary antithrombin deficiency is a rare congenital disorder associated with an increased risk of venous thromboembolism, particularly during high-risk situations such as surgery. Effective perioperative anticoagulation management is critical to prevent thromboembolic complications in these patients.

Case presentation

A 55-year-old female with a history of deep vein thrombosis and hereditary antithrombin deficiency presented with an anterior mediastinal tumor. Imaging findings suggested a benign cystic lesion; however, malignancy could not be completely excluded. A perioperative management strategy involving recombinant human antithrombin and heparin therapy was employed to safely perform uniportal robotic-assisted thymic cyst resection via a 4-cm incision i

SUBMITTER: Domen H 

PROVIDER: S-EPMC12719404 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature