Neuronal intranuclear inclusion disease presenting with recurrent dizziness and headache: a case report with 5-year follow-up.

ABSTRACT: Neuronal intranuclear inclusion disease (NIID) is a highly heterogeneous chronic neurodegenerative disease characterized by ataxia, extrapyramidal symptoms, peripheral neuropathy, autonomic nervous symptoms, and cognitive dysfunction. So far, recurrent dizziness and headache have been reported in cases of NIID. We report a case of a 71-year-old female patient with NIID, who was followed up for 5 years. The primary manifestations in this patient were episodic dizziness and headache, which are relatively nonspecific symptoms. Due to these characteristics, it is easy to misdiagnose or overlook the disease at the initial diagnosis. The patient exhibited characteristic high signal intensity at the corticomedullary junction on diffusion-weighted imaging (DWI) sequences of the head magnetic reson

SUBMITTER: Li L 

PROVIDER: S-EPMC12719417 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature