Visceral-to-subcutaneous fat ratio and risk of gallstones in Korean men: an observational study of 4,914 cases.

ABSTRACT:

Introduction

Gallstones are a prevalent gastrointestinal disorder influenced by metabolic factors and obesity. Visceral adiposity is metabolically active and proinflammatory, yet the role of the relative distribution of visceral and subcutaneous fat, quantified as the visceral-to-subcutaneous fat ratio (VSR), in gallstone formation remains unclear. This study aimed to investigate the association between VSR, measured by computed tomography (CT), and the prevalence of gallstones in Korean men.

Methods

This retrospective cross-sectional study included 4,914 Korean men who underwent both abdominopelvic CT and ultrasonography as part of routine health examinations. Visceral and subcutaneous fat areas were quantified at the L3 vertebral level using CT images, and participants wer

SUBMITTER: So H 

PROVIDER: S-EPMC12719422 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature