Developing a core outcome set for clinical trials of traditional Chinese medicine for rheumatoid arthritis.

ABSTRACT:

Objective

We developed a consensus-based core outcome set (COS) for Traditional Chinese Medicine clinical trials in rheumatoid arthritis (COS-TCM-RA) that to addresses heterogeneity in outcome measurement and reporting across studies.

Methods

We performed a comprehensive systematic review to establish a repository of clinical outcome set for TCM interventions in RA management. Then, a semi-structured interview was conducted to identify additional important outcomes from the patient's perspective. This was followed by an online three-round Delphi survey conducted with professionals to prioritize and refine clinically relevant outcomes from a previously developed longlist. Core entries were finalized based on three Delphi surveys and one expert consensus meeting.

Results

SUBMITTER: Yu B 

PROVIDER: S-EPMC12719495 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature