Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.

ABSTRACT:

Background

Traumatic brain injury (TBI) represents a major global health challenge. Several clinical studies have suggested that Xuebijing (XBJ)-a patented Chinese botanical drug preparation may confer neuroprotective and anti-inflammatory benefits in TBI. This systematic review and meta-analysis aimed to evaluate the therapeutic efficacy and safety of XBJ as an adjunctive treatment for TBI.

Materials and methods

A comprehensive search was performed across nine English and Chinese databases for randomized controlled trials (RCTs) evaluating XBJ in TBI patients, with records screened up to February 2025. Two independent reviewers conducted study selection and data extraction. Pooled estimates were calculated using fixed- or random-effects models, expressed as standardized mea

SUBMITTER: Sun Y 

PROVIDER: S-EPMC12719521 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature