Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies.

ABSTRACT: Current drugs against multiple human malignancies are limited, and developing new treatment strategies is improbable within a short time. So, considering the current situation, phytochemicals could be a viable option for developing chemotherapeutic agents for managing numerous types of malignancies. Therefore, we aimed to locate all phytochemicals of Eclipta prostrata and unravel their chemotherapeutic mechanisms and strategies individually. We defined 25 active compounds based on their anticancer activities after filtering through IMPPAT and literature search, and these compounds have chemotherapeutic activities against around 15 different human malignancies. In vitro and preclinical models support that the chemotherapeutic properties of phytochemicals derived from Eclipta prost

SUBMITTER: Hossain MS 

PROVIDER: S-EPMC12719615 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature