Clonal dissemination of ST19 Salmonella Typhimurium within a Chinese poultry breeding pyramid and One-Health implications.

ABSTRACT: Salmonella poses a major threat to global poultry production and food safety. However, the transmission dynamics of Salmonella within poultry breeding hierarchies and their implications for the One Health remain poorly understood. This study bridges this knowledge gap by conducting epidemiological surveillance and genomic analysis of ST19 S. Typhimurium across a poultry breeding chain in China, augmented by comparative genomics of publicly available strains from diverse ecological sources. From 1,047 samples collected in a breeding system in Fujian Province, we recovered 37 ST19 S. Typhimurium isolates. Genomic comparison showed high clonality (≤2 SNPs) across them, revealing clonal dissemination of ST19 S. Typhimurium within flocks in the poultry breeding pyramid. Evolutionary analysis wi

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12719724 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature