The impact of large-scale release of <i>Wolbachia</i> mosquitoes on dengue incidence in Campo Grande, Brazil: an ecological study.

ABSTRACT:

Background

The introduction of the wMel strain of Wolbachia into Aedes aegypti mosquitoes significantly reduces dengue virus transmission. We evaluated the impact of large-scale releases of Wolbachia-infected Ae. aegypti on dengue incidence in Campo Grande, a large urban city in the Central-West region of Brazil, in the first deployment of Wolbachia as an official dengue-control strategy by the Brazilian federal government.

Methods

Mosquitoes infected with wMel Wolbachia were released in geographically phased deployments throughout Campo Grande from December 2020 through December 2023. An ovitrap surveillance network monitored Wolbachia prevalence in local Ae. aegypti populations during and after releases.

SUBMITTER: de Morais Batista F 

PROVIDER: S-EPMC12719740 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature