Albuminuria is associated with worse outcomes in non-diabetics hospitalized with acute heart failure.

ABSTRACT:

Aims

Chronic kidney disease (CKD) increases the risk of morbidity and mortality in patients with heart failure (HF). Guidelines recommend assessing CKD using the urinary albumin-to-creatinine ratio (UACR), as albuminuria is strongly associated with the risk of incident HF and outcomes in chronic HF; however, its prognostic role in acute HF (AHF) remains unclear. We evaluated if albuminuria was associated with adverse outcomes in individuals hospitalized with AHF in Renal Optimization Strategies Evaluation-Acute Heart Failure (ROSE-AHF).

Methods

There were 339 participants with baseline UACR, 248 with UACR at Day 7 and 237 with both measurements for assessing change in UACR. Associations of baseline, Day 7 and change in UACR with all-cause mortality at 6 months and the compos

SUBMITTER: Takaoka Y 

PROVIDER: S-EPMC12719845 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature