Determinants of diuresis/natriuresis following ambulatory intravenous loop diuretics for worsening heart failure.

ABSTRACT:

Background

The use of intravenous (IV) diuretics in an outpatient setting may represent an alternative to conventional hospitalization. Our objective was to identify factors associated with diuretic response during ambulatory IV diuretic sessions in a population of advanced heart failure with no therapeutic project and a frequent flyer profile.

Method

All patients with 4-h IV diuretic sessions were analysed. An initial bolus followed a tailored protocol for continuous infusion based on the patient's baseline diuretic dose. Variables associated with diuresis and natriuresis following furosemide infusion were evaluated using mixed linear models.

Results

Seventy-six patients (mean age 75.4 years; LVEF 42.7%; eGFR 40.7 mL/min/1.73 m²) totalling 175 IV diuretic

SUBMITTER: Massin M 

PROVIDER: S-EPMC12719862 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature