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Topical medications for moderate-to-severe rosacea: protocol for a living systematic review and network meta-analysis.


ABSTRACT:

Introduction

Rosacea is a chronic skin condition characterised by papules, pustules, transient erythema (flushing), persistent erythema, telangiectasia and phymatous changes. Rosacea can be associated with substantial effects on quality of life. Rosacea is most commonly treated with topical therapy, but little is known about the relative efficacy of these treatment options.Since most randomised controlled trials of topical rosacea therapies do not include active comparators (ie, head-to-head comparisons), indirect comparisons must be made to understand the relative efficacy, safety and tolerability of these treatment options. The aim of this study is to conduct a living network meta-analysis evaluating topical therapies for moderate to severe rosacea. The results of this study can

SUBMITTER: Amstutz AV 

PROVIDER: S-EPMC12719891 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature