Detection and localization of radiation-induced pneumonitis using T 2 -mapping magnetic resonance imaging.

ABSTRACT:

Background and purpose

Radiation-induced pneumonitis (RP), a complication of lung radiotherapy, occurs at the earliest 6-12 weeks post-treatment. To assess RP, repeated computed tomography (CT)-scans post-radiotherapy are standard-of-care, but increase the patients' dose burden and secondary cancer risk. We propose a pipeline based on magnetic resonance imaging (MRI) T2 -mapping acquired 2-3 months post-radiotherapy that provides an automated patient stratification and initial segmentation of the RP lung volume.

Materials and methods

In total, 24 lung tumor patients received MRI-guided radiotherapy at a 0.35 T MR-Linac. MRI T2 -maps were retrieved from T2 -weighted images acquired at a diagnostic 1.5 T MRI-scanner 8-20 weeks post-radiotherapy. Mean baseline-corrected T2 -val

SUBMITTER: Klaar R 

PROVIDER: S-EPMC12720034 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature