Supplemental imaging modalities for breast cancer screening in women with dense breasts: A systematic review with economic considerations.

ABSTRACT:

Background

Underdiagnosis of breast cancer is a concern for women with dense breasts. This systematic review and meta-analysis evaluates the performance and cost-effectiveness of supplementary imaging modalities plus standard mammography, versus mammography alone, for detecting breast cancer in women with dense breasts.

Methods

We searched MEDLINE, Embase, Scopus, Cochrane Database, Web of Science, and CENTRAL for English-language studies published January 2014 to November 2024. Eligible studies compared the performance of a supplementary imaging modality with standard mammography in terms of cancer detection rate (CDR) in women with dense breasts undergoing screening. Risk of bias was assessed using QUADAS-2/QUADAS-C. Screening, data extraction, and quality assessment was c

SUBMITTER: Duggan SN 

PROVIDER: S-EPMC12720037 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature