Long-term safety and efficacy outcomes of the Acellular Tissue Engineered Vessel (ATEV) in extremity arterial trauma repair.

ABSTRACT:

Background

In cases of arterial injury, use of autologous vein for arterial repair is sometimes not feasible. We previously reported the short-term (ie, 30-day) outcomes of the Acellular Tissue Engineered Vessel (Symvess) in treating extremity vascular injuries. This study evaluates the long-term safety, efficacy, and mechanical durability of Symvess in patients with arterial trauma.

Methods

This prospective analysis focused on patients from the CLN-PRO-V005 clinical study who sustained noniatrogenic vascular injuries to the extremities, and for whom saphenous vein was not feasible for use. Patients received Symvess and were followed for up to 36 months. Primary outcomes include graft patency, limb salvage, adverse events, and mechanical durability, as assessed through clini

SUBMITTER: Curi MA 

PROVIDER: S-EPMC12720075 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature