Additively manufactured Tantalum-titanium alloys with optimized osteogenic and immunomodulatory properties for load-bearing orthopedic implants.

ABSTRACT: The Tantalum-Titanium (TaTi) alloys demonstrate significant potential as an orthopedic implant material. This study presents the development and comprehensive evaluation of novel additive manufactured TaTi alloys for orthopedic implant applications. Through a combination of materials engineering and biological validation, we designed pre-alloyed TaTi spherical powders with varying compositions (Ta25, Ta55, and Ta75) and fabricated dense and porous structures via selective laser melting (SLM). The SLM Ta55 alloy (Ti-55 wt %Ta) exhibited optimal mechanical properties, including a tensile strength of 891 MPa and an elastic modulus of 74 GPa, closely matching cortical bone. Surface characterization revealed that oxide layer (comprising Ta₂O₅/TiO₂) of SLM Ta55 p

SUBMITTER: Li J 

PROVIDER: S-EPMC12720114 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature