Characteristics of Retinal Oxygen Kinetics and Blood Flow in Myopia of Different Degrees.

ABSTRACT:

Purpose

To investigate the characteristics of retinal oxygen kinetics and blood flow across varying degrees of myopia and to explore associated factors.

Methods

This study included 146 eyes from 132 participants with varying refractive errors, classified by spherical equivalent (SE) into nonmyopia (NM; SE > -0.25 D, n = 45), mild-to-moderate myopia (MM; -0.25 D ≥ SE > -6.00 D, n = 48), and high myopia (HM; SE ≤ -6.00 D, n = 53). Retinal oxygen kinetics and blood flow were assessed in an optic-disc-centered annulus using a Multimodal Eye Functional Imaging and Analysis System. Group differences and correlation were evaluated with generalized estimating equations (GEEs), and nonlinear associations were examined using restricted cubic spline analysis.

Results

The mean ag

SUBMITTER: Ding X 

PROVIDER: S-EPMC12720189 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature