Environmental factors influencing hormone receptor positive breast cancer incidence: integrating chemical signatures from dust wipes with self-reported sources of exposure.

ABSTRACT:

Background

Breast cancer is a highly prevalent disease. Chemical exposures may contribute to breast cancer risk, though most chemicals to which humans are exposed remain understudied in breast cancer research.

Objective

This study tested the hypothesis that environmental chemicals present in households of women who do and do not develop breast cancer will have differential abundance, and that chemical profiles relate to self-reported sources of exposures.

Methods

Household dust wipe samples were collected at enrollment in the Sister Study cohort in 2003-2009. We evaluated a subsample of Sister Study participants who developed hormone receptor positive breast cancer within 10 years after enrollment (N = 40, "cases") and who remained breast cancer free during the same p

SUBMITTER: Koval LE 

PROVIDER: S-EPMC12720391 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature