Gonadotropin trajectories among postmenopausal women not using hormone therapy.

ABSTRACT:

Objective

While evidence suggests that gonadotropins may play an important role in aging-related changes in body composition and health outcomes, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) patterns have not been well characterized in older women. We characterized patterns of FSH and LH change over time after menopause.

Methods

In a sample of 291 postmenopausal women from the Women's Health Initiative OsteoPerio study who were not using hormone therapy, we estimated FSH and LH trajectories over a 20-year period using group-based trajectory modeling. Descriptive statistics identified differences according to hormone trajectory group.

Results

We estimated 3 FSH trajectories. The low FSH trajectory (36.1% of sample) showed had stable FSH, the moderate

SUBMITTER: Lima SM 

PROVIDER: S-EPMC12720887 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature